| Crews Frederick, boot and shoe maker, 23 New street |
| Cross Francis, victualler Prince of Wales, South street |
| Cross George Henry, victualler, Tontine Inn, 25 South street |
| Cross George Henry, basket maker, 55 Pyle street |
| Crossin Mrs. Jane, boot and shoe dealer, 7 St.. Thomas' square |
| Croucher Mrs. Frances, grocer and greengrocer, 96 Upper St. James' street |
| Croucher Robert, railway and general carrier, 47 Quay street |
| Crow Mr. William, 12 Trafalgar road |
| Crowther Rev. Benjamin (Congregational), 84 Carisbrooke road |
| Dabbs Mr. George Henry, Mount View cottage, St John's road |
| Dabbs George Henry Rogue, surgeon, 16 West street |
| Daking Mrs. Georgina 75 Carisbrooke road |
| Dallimore Henry, poulterer and game dealer, 29 Sea street |
| Dare Charles William, barrister-at-law, 28 Lugley street ; h East Standen, Arreton |
| Dashwood William, artist, 17 Lugley street |
| Daveis George, umbrella repairer and cutler, 71 Pyle street |
| Davis Mrs. Ann, apartments, 21 Chapel street |
| Davis, Edmonds & Clark, public accountants & auditors, 20 Holyrood street, and London, Portsmouth, Southampton and Brighton ; Samuel Wheeler, manager |
| Day William Henry, watchmaker and jeweller, 124 High street |
| Deacon John Raynes, linen and woollen draper, 25 St. James' square |
| Deacon William, basket & general hawker, Holly cottage, Barton |
| Dean William, leather cutter and shoe mercer, 8 St. Thomas' square |
| Deighton Philip, horse and cattle doctor and victualler, Crown Inn, 14 St. James' street |
| Denham Alfred, assistant overseer of Newport, and rate collector and deputy superintendent registrar of births, deaths and marriages, 90 Carisbrooke road |
| Denham John Francis, greengrocer, 105 St. James' square |
| Dennes Mrs. Elizabeth, midwife, 63 Pyle street |
| Dennes Mrs. Harriet, preparatory school, 9 Upper Pyle street |
| Dennett Richard, victualler, Princess Royal, Cross lanes |
| Denniss Mr. William, Appley villa, Shide cross |
| Denton Benjamin, boot and shoe maker, 41 Sea street |
| Denyer Edward, wine merchant (Wavell, Stephens & D.) ; h 133 High street |
| Denyer Thomas Edwin, victualler, Britannia, Hunny hill |
| Dibble William, clerk, 3 Broadlands terrace |
| Dixon John, picture-frame manufacturer, 45 Castle street |
| Dober Edwin, victualler, Beehive, 51 Lugley street |
| Doman Mrs. Frances, apartments, 32 Carisbrooke road |
| Donovan Andrew, dairyman, Hunny hill |
| Dore Charles, draper, 121 High street |
| Dore Henry Albert, coal merchant and horse and carriage letter, 61 Upper St. James' street |
| Dore Ralph, boot and shoe maker, 161-2 High street |
| Dore & Son, grocers and provision merchant, 160 High street |
| Dore William (D. & Son) ; h 160 High street |
| Dore William Walter (D. & Son) ; h Coppins bridge |
| Dove William, dairyman, South view |
| Downer Richard, shopkeeper, 12 Portland street |
| Downer William, boot and shoe maker, 100 Pyle street |
| Driver Rolls (D., Sharp & Co.) ; h Southampton |
| Driver, Sharp & Co., foreign timber, slate, pipe and cement merchants, Sea street, and Sandown and Cowes |
| Drudge Mrs. Amelia, beerhouse and shopkeeper, Barton |
| Dudley William, clock and watch maker & jeweller, 46 High street |